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Furthermore, in prostate cancer cells, miR-185 and miR-342 control lipogenesis and cholesterogenesis by reducing the expression of SREBP-1/2 and downregulating their targeted genes, including fatty acid synthase 96

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In vivo: In ob/ob mice, administration of Exendin-4 (10 g/kg or 20 g/kg) improved insulin sensitivity and significantly reduced serum glucose and hepatic steatosis

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